cBioPortal database analysis revealed that the promoter methylation levels of ABR (P = 6.91E-20, r = −0.41 for LUAD; P = 7.31E-8, r = −0.28 for LUSC) (Figure 5a), PREX1 (P = 1.786E-5, r = −0.20 for LUAD; P = 2.689E-3, r = −0.16 for LUSC) (Figure 5b), DOCK2 (P = 5.12E-10, r = −0.29 for LUAD; P = 4.785E-5, r = −0.21 for LUSC) (Figure 5c) and DOCK4 (P = 1.638E-6, r = −0.22 for LUAD; P = 1.609E-5, r = −0.22 for LUSC) (Figure 5d) were negatively correlated with mRNA expression in NSCLC. The gene discussed is DOCK4; the disease is non-small cell lung carcinoma.