NFE2L3 and neoplasm: Then, based on the differences in NFE2L3 gene copy numbers in the tumor, we divided GC patients into four groups, including ‘arm-level deletion’, ‘diploid/normal’, ‘arm-level gain’, and ‘high amplification’, which indicate the loss of an arm-level somatic copy, the normal number of copies, obtaining an arm-level Somatic copy, and many copies, respectively.