PTEN and systemic sclerosis: MiR‐21 is involved in keloids and systemic sclerosis, and overexpression of miR‐21 can increase fibroblast proliferation and EMT by regulating phosphatase, tensin homolog and protein kinase B.25In addition, TGF‐β1 promotes the expression of miR‐21, resulting in the inhibition of cell apoptosis and the acceleration of proliferation.25