Plasma proteomics from the same cohort revealed that dexamethasone suppressed ten host proteins (S100A8, S100A9, SERPINA1, SERPINA3, ORM1, LBP, VWF, PIGR, AZGP1 and CRP) that others have identified as biomarkers distinguishing severe COVID-19 cases from mild to moderate counterparts (full host proteome queryable via Online Atlas; Supplementary Table 3)37–40. This evidence concerns the gene SERPINA3 and COVID-19.