Using patient-derived xenograft tumors in the human IL-2 transgenic (hIL-2) NOG mouse model34, we showed that adoptively transferred peripheral blood T cells transduced with tumor antigen-specific TCR cloned from NeoScreen TILs mediated specific regression of established tumors in vivo (Fig. 2h,i and Extended Data Fig. 10c). The gene discussed is IL2; the disease is neoplasm.