AKT1 and Familial prostate cancer: The biological pathways included PI3K-Akt signaling, Proteoglycans in cancer, Leukocyte transendothelial migration, Tight junctions, AMPK signaling, Glycolysis/Gluconeogenesis, Phagosome, Pathways in cancer, Estrogen signaling, and Prostate cancer (Fig. 2A).