In contrast, glycoproteins involved in proteasome function (e.g. PSMD4)49,50, N-linked glycosylation (e.g., ENTPD5)51–54, glycan metabolism (e.g., NAGA)55, and receptor trafficking (e.g., LAMP1)56 were upregulated primarily in localized PCa and mPCa (Fig. 3C, upper image). Here, LAMP1 is linked to posterior cortical atrophy.