To further evaluate the relationships among SNHG17, miR-339-5p and FOSL2, pluc-FOSL2–3′ UTR-WT plasmids were cotransfected with miR-339-5p and SNHG17 into CRC cells for a luciferase assay, and the results indicated that ectopic SNHG17 expression could block the downregulation of luciferase activity induced by miR-339-5p (Fig. 4 h). The gene discussed is FOSL2; the disease is colorectal carcinoma.