The 5 types of tumor-infiltrating lymphocytes that exhibited important correlations with SRMS in READ included activated dendritic cells (Act DC, Spearman: r = 0.23, p = 6.6e− 07), CD56 dim natural killer cells (CD56 dim, Spearman: r = 0.214, p = 0.006), effector memory CD4 T cells (Tem CD4, Spearman: r = − 0.188, p = 0.011), type 2 T helper cells (Th2, Spearman: r = − 0.187, p = 0.0213), and type 17 T helper cells (Th17, Spearman: r = 0.178, p = 0.021). The gene discussed is CD4; the disease is neoplasm.