Cardiac arrest and ECPR markedly increased the plasma levels of IL-10, VEGF, leptin, TNF-α, IL-1β, IL-6, fractalkine, IL-5, IL-18, IP-10, IL-4, eotaxin, MIP-1α, IL-17α, IL-12, RANTES, G-CSF, LIX, and MCP-1. This evidence concerns the gene IL18 and cardiac arrest.