IRF3 and triple-A syndrome: We found that the extent of p-TBK1 and p-IRF3 was enhanced in abdominal aorta of AAA mice compared with the controls whereas it was reduced in abdominal aorta of AAA mice treated with oe-EZH2 comparted with oe-NC-treated AAA mice (p < 0.05) (Fig. 3C).