The results illustrated an increase in protein expression of cleaved caspase-3 and Bax yet a decrease in Bcl-2 protein expression in aortic tissues of AAA mice compared with the controls, while a reduction in the protein expression of cleaved caspase-3 and Bax yet an increase in Bcl-2 protein expression in aortic tissues of AAA mice overexpressing EZH2 compared with AAA mice overexpressing NC (p < 0.05) (Fig. 2C). This evidence concerns the gene CASP3 and triple-A syndrome.