In the stratified genetic association analysis by SNV genotype (Table 2), APOE4-associated risk of developing cognitive decline was significant in the low expression group of rs1279683 (AG+AA) (p = 0.035, OR = 2.02, 95% CI, 1.05–3.87), whereas APOE4-associated risk was not significant in the high expression group (GG) (p = 0.71, OR = 1.21, 95% CI, 0.44–3.37). Here, APOE is linked to Mental deterioration.