AFAP1L2 and cholangiocarcinoma: The XB130 expression was significantly positive relationship with LVSI (β = 0.2274, P = 0.005), intrahepatic type of CCA (β = 0.1623, P = 0.046), stage III of TNM staging (β = 0.4048, P < 0.001), stage IV of TNM staging (β = 0.2363, P = 0.012), T3 classification (β = 0.4314, P < 0.001), T4 classification (β = 0.3327, P < 0.001) and lymph node metastasis (β = 0.2060, P = 0.011).