ZHX2 and neoplasm: Next, to examine the ability of ZHX2 to maintain TNBC tumor growth in vivo, we first constructed firefly luciferase stably expressing MDA-MB-231 cells (MDA-MB-231-luc) followed by infecting these cells with doxycycline (Dox)-inducible control or ZHX2 shRNAs (Teton sh43, sh45).