In training cohort, univariable analysis found 12 candidate predictors that were closely associated with the all-cause mortality (Table 1), including ‘age’, ‘diabetes’, ‘CVD’, ‘serum Cr’, ‘Hgl’, ‘Hs-CRP’, ‘white blood cell’, ‘serum P’, ‘no caregiver’, ‘use of AVF’, ‘use of polyester cuffed semi-permanent dialysis catheter’ and ‘history of emergency temporary dialysis catheter placement’. The gene discussed is CRP; the disease is diabetes mellitus.