Although SOX9 and ACAN were significantly increased with CCM (P = .0043; P = .0006), AUT-fPC (P = .04 and P = .0033), and ALL-fPC (P = .005 and P = .0035) as compared with the negative control, a significant increase in COL2A1 was observed with CCM (P = .0016) and ALL-fPC (P = .014) but narrowly failed significance for AUT-fPC (P = .06) (Figure 2C). This evidence concerns the gene ACAN and acute lymphoblastic leukemia.