CD274 and brain cancer: Prostate and brain cancers with elevated Δ133TP53 mRNA levels have increased the numbers of immunosuppressive macrophages and CD4+ T cells (Kazantseva et al, 2018a, 2019) and have high levels of Programmed Cell Death 1 Ligand 1 (PD‐L1), encoding one of the surface molecules that inhibit anti‐tumour T‐cell responses (Karwacz et al, 2011).