TP53 and infection: Two independent studies have showed that p53 enhanced adenovirus replication by increasing expression of late‐viral genes (Royds et al, 2006; Wright & Leppard, 2013), despite p53 being degraded by a complex of E1b55 kD and E4orfE6 protein during the early phase of infection ((Querido et al, 2001); Table 1).