AGT and abdominal aortic aneurysm: Although based on the initial description of aortic lesions in high salt intake-induced angiotensin II overproducing mice by Nishijo et al35 in 1998, the model as we know it today is attributed to Daugherty et al,7 who implanted osmotic minipumps and published on “Unexpectedly, pronounced abdominal aortic aneurysms were present in ApoE−/− mice infused with Ang II” in 2000 while looking for a way to increase blood pressure in atherosclerotic mouse models.7