ACE2 and Thrombocytopenia: Several pathophysiological mechanisms are implicated in this process, including angiotensin-converting enzyme 2 (ACE2)-dependent pathways (with ACE being the receptor for SARS-CoV-2 that facilitates viral entry and replication), cytokine storm activation, hypoxemia, drug toxicities, stress-induced vascular dysfunction, thrombocytopenia, prolonged prothrombin time and fibrinolysis (4–6).