Older age, elevated NYHA Classification, a higher Uric acid, absolute neutrophil count, QRS, Blood urea nitrogen, direct bilirubin, Cystatin C, free thyroxine, NT-proBNP, Cardiac troponin, red blood cell distribution width, Serum chlorine, Creatinine; the presence of previous diabetes mellitus and noβ-blockers have increased the risk of CHF-related mortality. This evidence concerns the gene NPPB and diabetes mellitus.