Elevated serum CA 125 values were observed in 57 (60.0%) patients in the AL-CA group, with a mean value of 134.9 ± 148.6 KU/L, in 6 (54.5%) patients in the TTR-CA group, with a mean value of 112.4 ± 134.7 KU/L, in 16 (39.0%) patients in the CHF group with a mean value of 45.7 ± 44.9 KU/L and in 3 (7.7%) patients in the MM group with a mean value of 18.9 ± 20.9 KU/L (p < 0.01), Supplementary Figure 1. The gene discussed is TTR; the disease is congestive heart failure.