Interestingly, the higher dose of cyto-IL-15 (10 μg) derived from IL-15 purified using mild denaturing conditions had a similar effect in terms of tumor growth delay with the same dose of cyto-IL-15 Gen derived from IL-15 recovered from inclusion bodies (cyto-IL-15 Gen) and a slightly greater effect in terms of mice survival (32 vs. 28 days). Here, IL15 is linked to neoplasm.