ACHE and Alzheimer disease: In this regard, the efficacy of different antioxidants that prevent and reverse AD when combined with adequate diets has been seen (78), highlighting vitamin C (79), α-lipoic acid (80) or the polyphenols epigallocatechin gallate and resveratrol (which can also prevent the neurotoxic effects of β-amyloid protein) (81), while drugs such as donepezil, galantamine and rivastigmine, which act as inhibitors of acetylcholinesterase derived from the accumulation of β-amyloid, could be more effective in advanced stages of the disease (82).