Univariate and multivariate analysis showed that PG-SGA score (p = 0.001, HR = 1.638, 95%CI: 1.259–2.441), pre-albumin (p = 0.033, HR = 0.687, 95%CI: 0.548–0.861), BMI(p = 0.011, HR = 1.321, 95%CI: 0.925–1.874), NIH classification (p = 0.000, HR = 2.805, 95%CI: 2.241–3.510), nutritional therapy(p = 0.012, HR = 1.267, 95%CI: 0.987–1.762) were independent risk factors affecting the 5-year OS rate of newly diagnosed GIST patients (Table 6). Here, ALB is linked to gastrointestinal stromal tumor.