GCLC and asthma: On the other hand, Sudini et al. (43) did not find any difference in transcript levels of Nrf2 target antioxidant genes HO-1, NQO1, glutamate cysteine ligase catalytic subunit (GCLC), and glutamate cysteine ligase modifier subunit (GCLM) in nasal epithelial cells and peripheral blood mononuclear cells (PBMCs) between the treatment with 100 g broccoli sprouts for three consecutive days and the placebo (alfalfa sprouts) among adults with asthma and allergic sensitization.