CTNNB1 and hemoglobin measurement: In addition, a study also found that METTL3, which is significantly upregulated in hepatoblastoma (HB), can enhance the stability of catenin (cadherin-associated protein) beta 1 (CTNNB1) mRNA in a m6A modification-dependent manner and, subsequently, activate Wnt/β-catenin signaling to expedite HB progression (Liu L. et al., 2019).