Among them, WTAP leads to the posttranscriptional suppression of ETS proto-oncogene 1 (ETS1) in a m6A-dependent manner by using Hu-Antigen R (HuR) as an RNA stabilizer, thus regulating the HCC cell cycle distribution of G2/M phase in a p21/p27-dependent manner to speed up HCC progression (Chen et al., 2019). Here, ETS1 is linked to hepatocellular carcinoma.