For example, the FDA-approved ethyl ester form of meclofenamic acid (MA), a non-steroidal anti-inflammatory drug named MA2, was found to be an FTO inhibitor that increased the m6A modification level of mRNA in glioblastoma cells, thus inhibiting tumor progression and extending the lifespan of GSC-transplanted mice (Xiao et al., 2020). Here, FTO is linked to glioblastoma.