Using the Léger's and LM-LBM equations, the prevalence of central obesity, general overweight/obesity, elevated BP, low HDL-C, elevated atherogenic index, and CRP > 3 mg/L was significantly higher in males at the upper tail of eGFR distribution vs. the lower tail (Table 6). The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.