On the other hand, Deeplex Myc-TB found two mutations in Rv0678 in BDQ-S strains, one with a double mutation I67T-Y92STOP with a proportion of variant of 30% (Supplementary Table 1), and the other with the E55D substitution (Table 4) which is a SNV preserving the acidic function with probably no significant impact on the efflux function of Rv0678, as previously suggested (Martinez et al., 2018). Here, MYC is linked to tuberculosis.