NK and T-cells express Sdc1, VEGFR2, CXCR4, AC7 and HPSE and their LFA-1-mediated migration in in vitro invasion assays is dramatically increased by SSTNVEGFR2 while at the same time the peptide inhibits the VLA-4-mediated invasion of myeloma cells (64). Here, HPSE is linked to plasma cell myeloma.