SIRPA and neoplasm: “Don’t eat me” signaling pathways, such as CD47-SIRPα, the MHC-I-LILRB1 axis, and the CD24-SIGLEC-10 axis can be expressed by all types of macrophages (48) and play crucial roles in inhibiting macrophage phagocytosis of tumor cells in numerous cancer types (13, 15, 17, 29).