TGFB1 and colorectal carcinoma: The miRNA miR-486-5p plays a protective role against CRC, and it acts by obstructing the expression of neuropilin‐2 (NRP-2) (44), which is known to interfere with the epithelial-mesenchymal transition (EMT) of CRC cells via crosstalk with transforming growth factor β1 (TGF-β1) (33).