There are few reports on the role of mascRNA, which may participate in cardiovascular innate immunity by affecting fas ligand (FASLG), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), etc. (29) It may also be part of the molecular mechanism of function in cancer to regulate the glutaminyl-tRNA synthetase (QARS) protein levels and promote global protein translation and cell proliferation (30). This evidence concerns the gene TNF and cancer.