Furthermore, in xenograft tumor models of Eμ-Myc lymphoma, the loss of one TP53 allele significantly accelerated Myc-induced classical Eμ-Myc lymphoma formation; however, the loss of one ALOX12 allele suppressed p53-mediated ferroptosis and eliminated p53-dependent tumor growth inhibition. This evidence concerns the gene TP53 and erythema multiforme.