IDH1 and central nervous system cancer: However, multivariate logistic regression analysis revealed that age at diagnosis (OR 0.925, [95% CI], 0.875–0.978, p = 0.006), KPS (OR 1.106, [95% CI 1.023–1.196], p = 0.011), tumor grade (OR 17.429, [95% CI 4.618–67.790], p < 0.001), EOR (OR 9.894, [95% CI 2.332–41.979], p = 0.002), and IDH1 (OR 0.049, [95% CI 0.006–0.432], p = 0.007) were independent risk factors of short-term glioma recurrence (Table 2).