BTK and neuroblastoma: For example, Li et al. reported that the expression of BTK is detectable in human neuroblastoma cell lines IMR32, LAN2, NBL-S and SHSY5Y (83), and Pikatan et al. also detected the expression of BTK in human neuroblastoma cell lines SK-N-BE2 and SH-5YSY by Western blot analysis (30).