Similarly, some protein studies performed in a low number of cases showed no CCR7 in B-ALL (18, 19) while, in others series, expression was detected in specific subtypes of B-ALL, mainly in pediatric Burkitt ́s-like B-ALL and in one third of pediatric pro-B, early-pre-B, and pre-B ALL (20). This evidence concerns the gene CCR7 and acute lymphoblastic leukemia.