CCR7 and neoplasm: However, our knowledge on CCR7 biology in blood cancers is still scant and additional efforts are needed to solve relevant questions such as around the major mechanisms regulating CCR7 (over)expression, how CCR7 contributes to tumor growth during the first tumorigeneic events, or what the exact contributions of CCR7 in accessory cells in early cancer events or during different stages of target tissue colonization are.