According to Figure 2 and Supplementary Table S4, it could be found that the expression level of RPN1 was upregulated in various subtypes of breast cancer including invasive breast carcinoma, mucinous breast carcinoma, medullary breast carcinoma, invasive ductal breast carcinoma, and ductal breast carcinoma in Curtis’s dataset (22). This evidence concerns the gene RPN1 and invasive ductal breast carcinoma.