According to the results (Figure 2), 37.5% (17 of 45) of the MTC referral index patients were found to have eight distinct RET germline mutations, including p.C634R (35.3%), p.M918T (17.6%), p.C634Y (11.8%), p.C634F (5.9%), p.C611Y (5.9%), p.C618R (5.9%), p.C630R (5.9%), p.L790F (5.9%), and an uncertain variant p.V648I (5.9%). Here, RET is linked to medullary thyroid gland carcinoma.