BDNF and pancreatic adenocarcinoma: However, BDNF played a detrimental role in bladder urothelial carcinoma (PFS: HR = 1.06, 95%CI = 1.00–1.11, p < 0.001), colon adenocarcinoma (PFS: HR = 1.44, 95%CI = 1.22–1.69, p < 0.001), and PAAD (PFS: HR = 1.29, 95%CI = 1.07–1.55, p < 0.001).