HMGB3 was upregulated in 11 other types of cancers, including breast invasive carcinoma (BRCA), esophageal carcinoma (ESCA), head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), ovarian serous cystadenocarcinoma (OV), prostate adenocarcinoma (PRAD), testicular germ cell tumors (TGCT), and uterine corpus endometrial carcinoma (UCEC). Here, HMGB3 is linked to squamous cell lung carcinoma.