HLA-DRB1 and rheumatoid arthritis: A significant positive interaction between rs4947332 (HLA-DRB1) and rs5997893 (MIR3928) with a significantly inflated OR = 2.83 (95%CI: 1.75–4.58, p = 1.36 × 10−5, Table 4) for double risk allele carriers, indicating the importance of HLA and non-HLA genetic variation interaction in RA susceptibility.