Overexpression of COL5A1 may promote metastasis of lung adenocarcinoma (Liu et al., 2018) and the progression of muscle-invasive bladder cancer (Ewald et al., 2013) and may increase the risk of hematogenous and lymphatic metastasis in serous ovarian cancer (Yue et al., 2019). Here, COL5A1 is linked to ovarian serous adenocarcinoma.