For example, SBF2-AS1, CCAT1, UCA1 regulate miR-188-5p, miR-155, miR-125a, thereby up-regulating the expression of target genes ZFP9, c-Myc, and HK2 promotes the proliferation of AML cells (Chen et al., 2016; Zhang et al., 2018; Tian et al., 2019). This evidence concerns the gene HK2 and acute myeloid leukemia.