Univariate Cox regression analysis showed that 4 DE-FLs (AC016027.1, AC099850.3, ELFN1-AS1, and VPS9D1-AS1) were associated with OS in CRC, except VPS9D1-AS1 played a risk factor with HR > 1, the others acted as protectors with HR < 1 (Figure 3A). The gene discussed is ELFN1; the disease is colorectal carcinoma.