Focusing on helper T cells, we observed differential distribution patterns of TH1 (CD45+CD3+CD8−Foxp3−Tbet+) in tumor cell nests and TH2 (CD45+CD3+CD8−Foxp3−GATA3+) in the intratumoral stroma (Figure 2B and Supplementary Figure 2A). The gene discussed is PTPRC; the disease is neoplasm.