ATP13A2 and Kufor-Rakeb syndrome: Recently, another study reported that HDAC6 was recruited by ATP13A2, whose mutations are associated with Kufor-Rakeb syndrome (KRS), an autosomal recessive form of juvenile-onset atypical Parkinson’s disease (PD), which is known as Parkinson’s disease-9, to deacetylate cortactin and promote autophagosome-lysosome fusion and autophagy (88).