SLIT2 and neoplasm: As shown in Figure 1A, PBS-treated PyMT (PBS pre mean ± SEM 776.04 ± 246.4 vs. PBS post 2584.8 ± 447.8 mm3, n = 5, #p < 0.005) mice showed an approximately 2.5x increase in tumor volume at the end of the study, whereas Slit2-treated mice did not show a significant change in tumor volume (Slit2 pre mean ± SEM 858.3 ± 442.1 vs. Slit2 post 997.4 ± 117.2 mm3, n = 5, p > 0.05), as tested by paired t-test.