To further investigate the relationships between PMEPA1 and the different immune cells, we calculated the infiltration levels of TIICs including TAMs, cancer associated fibroblasts (CAFs), myeloid-derived suppressor cells (MDSCs), monocytes, neutrophils, tregs, myeloid dendritic cells (DCs), NK cells, B cells, CD4+ T cells, and CD8+ T cells using eight independent algorithms in TIMER (Table S12 and Figure S4). Here, CD4 is linked to cancer.