Multiple studies point out how impaired sexuality may be either predicted by or correlated to heavier psychotic symptomatology and longer DUP, without showing any association with hormones blood levels, like prolactin, or testosterone (46, 47, 50, 52), although hyperprolactinemia may be a clinical feature of drug-naïve people with FEP (68). This evidence concerns the gene PRL and hyperprolactinemia.