Cyanidin could be used for rheumatoid arthritis (RA) treatment as Interleukin 17A/IL-17 receptor A (IL-17/17RA) signaling targeted therapy and could alleviate clinical symptoms, synovial growth, immune cell infiltration, and bone erosion in adjuvant-induced arthritis (AA) rats (Samarpita et al., 2020; Samarpita and Rasool, 2021). The gene discussed is IL17RA; the disease is rheumatoid arthritis.