VEGFA and Arthritis: Our previous study showed that ATO could exhibit antirheumatic effects via the regulation of dysregulated autophagy (Wang et al., 2019) and dysimmunity (Li et al., 2019); in particular, ATO was verified to operate an anti-angiogenic effect through the VEGF-centered functional module and significantly improved arthritis both in cell and the CIA mice model (Zhang et al., 2017).